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Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters
Extracellular matrix (ECM) remodeling dynamically occurs to accommodate adipose tissue expansion during obesity. One non-fibrillar component of ECM, biglycan, is released from the matrix in response to tissue stress; the soluble form of biglycan binds to toll-like receptor 2/4 on macrophages, causin...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4964581/ https://ncbi.nlm.nih.gov/pubmed/27465988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30609 |
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