Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich Cancer

The 18-kDa translocator protein (TSPO) levels are associated with brain, breast, and prostate cancer progression and have emerged as viable targets for cancer therapy and imaging. In order to develop highly selective and active ligands with a high affinity for TSPO, imidazopyridine-based TSPO ligand...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Choi, Ji Young, Iacobazzi, Rosa Maria, Perrone, Mara, Margiotta, Nicola, Cutrignelli, Annalisa, Jung, Jae Ho, Park, Do Dam, Moon, Byung Seok, Denora, Nunzio, Kim, Sang Eun, Lee, Byung Chul
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964461/
https://ncbi.nlm.nih.gov/pubmed/27399688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071085
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