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Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques

Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone (Dp44mT) exhibits significant antitumor activity. However, the mechanism of its pharmacological interaction with human serum albumin (HSA) and DNA remains poorly understood. Here, we aimed to elucidate the interactions of Dp44mT with HSA and DNA u...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Xu, Zhongjie, Liu, Youxun, Zhou, Sufeng, Fu, Yun, Li, Changzheng
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964418/
https://ncbi.nlm.nih.gov/pubmed/27376275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071042
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