Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway

The epithelial-to-mesenchymal transition (EMT) is a crucial cellular event in wound healing, tissue repair, and cancer progression in adult tissues, with the interactions with numerous signals. In this study, we aimed to determine whether bleomycin (BLM), an agent that causes pulmonary fibrosis, ind...

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Bibliographic Details
Published in:J Cancer
Main Authors: Chen, Kui-Jun, Li, Qing, Wen, Cang-mei, Duan, Zhao-Xia, Zhang, Jie yuan, Xu, Chuan, Wang, Jian-Min
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964140/
https://ncbi.nlm.nih.gov/pubmed/27471572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15566
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