Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway

The epithelial-to-mesenchymal transition (EMT) is a crucial cellular event in wound healing, tissue repair, and cancer progression in adult tissues, with the interactions with numerous signals. In this study, we aimed to determine whether bleomycin (BLM), an agent that causes pulmonary fibrosis, ind...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Chen, Kui-Jun, Li, Qing, Wen, Cang-mei, Duan, Zhao-Xia, Zhang, Jie yuan, Xu, Chuan, Wang, Jian-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964140/
https://ncbi.nlm.nih.gov/pubmed/27471572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15566
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