Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway

The epithelial-to-mesenchymal transition (EMT) is a crucial cellular event in wound healing, tissue repair, and cancer progression in adult tissues, with the interactions with numerous signals. In this study, we aimed to determine whether bleomycin (BLM), an agent that causes pulmonary fibrosis, ind...

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Vydáno v:J Cancer
Hlavní autoři: Chen, Kui-Jun, Li, Qing, Wen, Cang-mei, Duan, Zhao-Xia, Zhang, Jie yuan, Xu, Chuan, Wang, Jian-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964140/
https://ncbi.nlm.nih.gov/pubmed/27471572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15566
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