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Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic Shock in Hepatocellular Carcinoma

Background: Hypotonic shock induces cytocidal effects through cell rupture, and cancer therapy based on this mechanism has been clinically administered to hepatocellular carcinoma patients. We herein investigated the effectiveness of hypotonic shock combined with the inhibition of regulatory volume...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Kudou, Michihiro, Shiozaki, Atsushi, Kosuga, Toshiyuki, Ichikawa, Daisuke, Konishi, Hirotaka, Morimura, Ryo, Komatsu, Shuhei, Ikoma, Hisashi, Fujiwara, Hitoshi, Okamoto, Kazuma, Hosogi, Shigekuni, Nakahari, Takashi, Marunaka, Yoshinori, Otsuji, Eigo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964136/
https://ncbi.nlm.nih.gov/pubmed/27471568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15181
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