Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic Shock in Hepatocellular Carcinoma

Background: Hypotonic shock induces cytocidal effects through cell rupture, and cancer therapy based on this mechanism has been clinically administered to hepatocellular carcinoma patients. We herein investigated the effectiveness of hypotonic shock combined with the inhibition of regulatory volume...

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Bibliographic Details
Published in:J Cancer
Main Authors: Kudou, Michihiro, Shiozaki, Atsushi, Kosuga, Toshiyuki, Ichikawa, Daisuke, Konishi, Hirotaka, Morimura, Ryo, Komatsu, Shuhei, Ikoma, Hisashi, Fujiwara, Hitoshi, Okamoto, Kazuma, Hosogi, Shigekuni, Nakahari, Takashi, Marunaka, Yoshinori, Otsuji, Eigo
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964136/
https://ncbi.nlm.nih.gov/pubmed/27471568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15181
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