BRCA-associated protein 1 mutant cholangiocarcinoma: an aggressive disease subtype

BACKGROUND: BRCA-associated protein 1, an enzyme encoded by the BAP1 gene, is commonly mutated in uveal melanoma, mesothelioma, and renal cancers. Tumors with BAP1 mutation follow an aggressive course. BAP1 mutations have also been observed in cholangiocarcinoma (CCA). The clinical phenotype of BAP1...

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Vydáno v:J Gastrointest Oncol
Hlavní autoři: Al-Shamsi, Humaid O., Anand, Deepa, Shroff, Rachna T., Jain, Apurva, Zuo, Mingxin, Conrad, Claudius, Vauthey, Jean-Nicolas, Javle, Milind M.
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963380/
https://ncbi.nlm.nih.gov/pubmed/27563445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.03.05
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