BRCA-associated protein 1 mutant cholangiocarcinoma: an aggressive disease subtype

BACKGROUND: BRCA-associated protein 1, an enzyme encoded by the BAP1 gene, is commonly mutated in uveal melanoma, mesothelioma, and renal cancers. Tumors with BAP1 mutation follow an aggressive course. BAP1 mutations have also been observed in cholangiocarcinoma (CCA). The clinical phenotype of BAP1...

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Bibliografische gegevens
Gepubliceerd in:J Gastrointest Oncol
Hoofdauteurs: Al-Shamsi, Humaid O., Anand, Deepa, Shroff, Rachna T., Jain, Apurva, Zuo, Mingxin, Conrad, Claudius, Vauthey, Jean-Nicolas, Javle, Milind M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AME Publishing Company 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963380/
https://ncbi.nlm.nih.gov/pubmed/27563445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.03.05
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