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OmpA signal peptide leads to heterogenous secretion of B. subtilis chitosanase enzyme from E. coli expression system

The production of secreted recombinant proteins from E. coli is pivotal to the biotechnological industry because it reduces the cost of downstream processing. Proteins destined for secretion contain an N-terminal signal peptide that is cleaved by secretion machinery in the plasma membrane. The resul...

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Veröffentlicht in:Springerplus
Hauptverfasser: Pechsrichuang, Phornsiri, Songsiriritthigul, Chomphunuch, Haltrich, Dietmar, Roytrakul, Sittiruk, Namvijtr, Peenida, Bonaparte, Napolean, Yamabhai, Montarop
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963352/
https://ncbi.nlm.nih.gov/pubmed/27516938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-2893-y
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