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Dimensionality and spreading influence MSC YAP/TAZ signaling in hydrogel environments

Improved fundamental understanding of how cells interpret microenvironmental signals is integral to designing better biomaterial therapies. YAP/TAZ are key mediators of mechanosensitive signaling; however, it is not clear how they are regulated by the complex interplay of microenvironmental factors...

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發表在:Biomaterials
Main Authors: Caliari, Steven R., Vega, Sebastián L., Kwon, Michelle, Soulas, Elizabeth M., Burdick, Jason A.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963302/
https://ncbi.nlm.nih.gov/pubmed/27429252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.06.061
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