Dose and timing of N-cadherin mimetic peptides regulate MSC chondrogenesis within hydrogels

The transmembrane glycoprotein N-cadherin (NCad) mediates cell–cell interactions found during mesenchymal condensation and chondrogenesis. Here, NCad-derived peptides (i.e., HAV) were incorporated into hyaluronic acid (HA) hydrogels with encapsulated mesenchymal stem cells (MSCs). Since the dose and...

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Bibliographic Details
Published in:Adv Healthc Mater
Main Authors: Kwon, Mi. Y., Vega, Sebastian. L., Gramlich, William. M., Kim, Minwook., Mauck, Robert. L., Burdick, Jason. A.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296766/
https://ncbi.nlm.nih.gov/pubmed/29359863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201701199
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