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Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules

Local translation at the synapse plays key roles in neuron development and activity-dependent synaptic plasticity. mRNAs are translocated from the neuronal soma to the distant synapses as compacted ribonucleoparticles referred to as RNA granules. These contain many RNA-binding proteins, including th...

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Publicat a:PLoS Genet
Autors principals: El Fatimy, Rachid, Davidovic, Laetitia, Tremblay, Sandra, Jaglin, Xavier, Dury, Alain, Robert, Claude, De Koninck, Paul, Khandjian, Edouard W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963131/
https://ncbi.nlm.nih.gov/pubmed/27462983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006192
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