Dicer-Derived MicroRNAs Are Utilized by the Fragile X Mental Retardation Protein for Assembly on Target RNAs

In mammalian cells, fragile X mental retardation protein (FMRP) has been reported to be part of a microRNA (miRNA)-containing effector ribonucleoprotien (RNP) complex believed to mediate translational control of specific mRNAs. Here, using recombinant proteins, we demonstrate that human FMRP can act...

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Bibliographic Details
Main Authors: Plante, Isabelle, Davidovic, Laetitia, Ouellet, Dominique L., Gobeil, Lise-Andrée, Tremblay, Sandra, Khandjian, Edouard W., Provost, Patrick
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698263/
https://ncbi.nlm.nih.gov/pubmed/17057366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/JBB/2006/64347
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