Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis

PURPOSE: Posterior fossa ependymoma comprises two distinct molecular variants termed EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic value of cytoreductive surgery and radiation therapy for posterior fossa ependymoma after accounting for molecular subgroup is no...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Ramaswamy, Vijay, Hielscher, Thomas, Mack, Stephen C., Lassaletta, Alvaro, Lin, Tong, Pajtler, Kristian W., Jones, David T.W., Luu, Betty, Cavalli, Florence M.G., Aldape, Kenneth, Remke, Marc, Mynarek, Martin, Rutkowski, Stefan, Gururangan, Sridharan, McLendon, Roger E., Lipp, Eric S., Dunham, Christopher, Hukin, Juliette, Eisenstat, David D., Fulton, Dorcas, van Landeghem, Frank K.H., Santi, Mariarita, van Veelen, Marie-Lise C., Van Meir, Erwin G., Osuka, Satoru, Fan, Xing, Muraszko, Karin M., Tirapelli, Daniela P.C., Oba-Shinjo, Sueli M., Marie, Suely K.N., Carlotti, Carlos G., Lee, Ji Yeoun, Rao, Amulya A. Nageswara, Giannini, Caterina, Faria, Claudia C., Nunes, Sofia, Mora, Jaume, Hamilton, Ronald L., Hauser, Peter, Jabado, Nada, Petrecca, Kevin, Jung, Shin, Massimi, Luca, Zollo, Massimo, Cinalli, Giuseppe, Bognár, László, Klekner, Almos, Hortobágyi, Tibor, Leary, Sarah, Ermoian, Ralph P., Olson, James M., Leonard, Jeffrey R., Gardner, Corrine, Grajkowska, Wieslawa A., Chambless, Lola B., Cain, Jason, Eberhart, Charles G., Ahsan, Sama, Massimino, Maura, Giangaspero, Felice, Buttarelli, Francesca R., Packer, Roger J., Emery, Lyndsey, Yong, William H., Soto, Horacio, Liau, Linda M., Everson, Richard, Grossbach, Andrew, Shalaby, Tarek, Grotzer, Michael, Karajannis, Matthias A., Zagzag, David, Wheeler, Helen, von Hoff, Katja, Alonso, Marta M., Tuñon, Teresa, Schüller, Ulrich, Zitterbart, Karel, Sterba, Jaroslav, Chan, Jennifer A., Guzman, Miguel, Elbabaa, Samer K., Colman, Howard, Dhall, Girish, Fisher, Paul G., Fouladi, Maryam, Gajjar, Amar, Goldman, Stewart, Hwang, Eugene, Kool, Marcel, Ladha, Harshad, Vera-Bolanos, Elizabeth, Wani, Khalida, Lieberman, Frank, Mikkelsen, Tom, Omuro, Antonio M., Pollack, Ian F., Prados, Michael, Robins, H. Ian, Soffietti, Riccardo, Wu, Jing, Metellus, Phillipe, Tabori, Uri, Bartels, Ute, Bouffet, Eric, Hawkins, Cynthia E., Rutka, James T., Dirks, Peter, Pfister, Stefan M., Merchant, Thomas E., Gilbert, Mark R., Armstrong, Terri S., Korshunov, Andrey, Ellison, David W., Taylor, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962737/
https://ncbi.nlm.nih.gov/pubmed/27269943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.65.7825
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