Iron Limitation Triggers Early Egress by the Intracellular Bacterial Pathogen Legionella pneumophila

Legionella pneumophila is an intracellular bacterial pathogen that replicates in alveolar macrophages, causing a severe form of pneumonia. Intracellular growth of the bacterium depends on its ability to sequester iron from the host cell. In the L. pneumophila strain 130b, one mechanism used to acqui...

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Bibliographic Details
Published in:Infect Immun
Main Authors: O'Connor, Tamara J., Zheng, Huaixin, VanRheenen, Susan M., Ghosh, Soma, Cianciotto, Nicholas P., Isberg, Ralph R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962634/
https://ncbi.nlm.nih.gov/pubmed/27185787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01306-15
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