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Complex relation of HLA-DRB1*1501, age at menarche, and age at multiple sclerosis onset

OBJECTIVE: To examine the relationship between 2 markers of early multiple sclerosis (MS) onset, 1 genetic (HLA-DRB1*1501) and 1 experiential (early menarche), in 2 cohorts. METHODS: We included 540 white women with MS or clinically isolated syndrome (N = 156 with genetic data available) and 1,390 w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurol Genet
Hauptverfasser: Bove, Riley, Chua, Alicia S., Xia, Zongqi, Chibnik, Lori, De Jager, Philip L., Chitnis, Tanuja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962522/
https://ncbi.nlm.nih.gov/pubmed/27504495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000088
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