Placental transfer and mammary excretion of a novel angiotensin receptor blocker fimasartan in rats

BACKGROUND: Fimasartan (FMS) is a potent angiotensin receptor blocker for the treatment of mild to moderate hypertension. This study aimed to evaluate the transfer of FMS to fetus and breast milk in rats. METHODS: In order to study the transfer to the fetus and nursing pup, pregnant and nursing mate...

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Pubblicato in:BMC Pharmacol Toxicol
Autori principali: Kim, Tae Hwan, Kim, Min Gi, Shin, Soyoung, Chi, Yong-Ha, Paik, Soo-Heui, Lee, Joo-Han, Yoo, Sun Dong, Youn, Yu Seok, Bulitta, Jürgen B., Joo, Sang Hoon, Jeong, Seok Won, Weon, Kwon-Yeon, Shin, Beom Soo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962410/
https://ncbi.nlm.nih.gov/pubmed/27459959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0080-y
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