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Interactions Between Sirolimus and Anti-Inflammatory Drugs: Competitive Binding for Human Serum Albumin

Purpose: The aim of the present study was investigating the effects of three anti-inflammatory drugs, on Sirolimus protein biding. The binding site of Sirolimus on human serum albumin (HSA) was also determined. Methods: Six different concentrations of Sirolimus were separately exposed to HSA at pH 7...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Khodaei, Arash, Bolandnazar, Soheila, Valizadeh, Hadi, Hasani, Leila, Zakeri-Milani, Parvin
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961981/
https://ncbi.nlm.nih.gov/pubmed/27478785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2016.031
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