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The Effects of Lyophilization on the Physico-Chemical Stability of Sirolimus Liposomes

Purpose: The major limitation in the widespread use of liposome drug delivery system is its instability. Lyophilization is a promising approach to ensure the long-term stability of liposomes. The aim of this study was to prepare sirolimus-loaded liposomes, study their stability and investigate the e...

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Detalhes bibliográficos
Main Authors: Ghanbarzadeh, Saeed, Valizadeh, Hadi, Zakeri-Milani, Parvin
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846045/
https://ncbi.nlm.nih.gov/pubmed/24312808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5681/apb.2013.005
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