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D-optimal Design for Preparation and Optimization of Fast Dissolving Bosentan Nanosuspension

Purpose: Bosentan is a drug currently taken orally for the treatment of pulmonary arterial hypertension. However, the water solubility of bosentan is very low, resulting in low bioavailability. The aim of this study was preparation and optimization of bosentan nanosuspension to improve solubility an...

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Bibliografiska uppgifter
I publikationen:Adv Pharm Bull
Huvudupphovsmän: Ghasemian, Elham, Motaghian, Parisa, Vatanara, Alireza
Materialtyp: Artigo
Språk:Inglês
Publicerad: Tabriz University of Medical Sciences 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961979/
https://ncbi.nlm.nih.gov/pubmed/27478783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2016.029
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