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D-optimal Design for Preparation and Optimization of Fast Dissolving Bosentan Nanosuspension

Purpose: Bosentan is a drug currently taken orally for the treatment of pulmonary arterial hypertension. However, the water solubility of bosentan is very low, resulting in low bioavailability. The aim of this study was preparation and optimization of bosentan nanosuspension to improve solubility an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Adv Pharm Bull
Prif Awduron: Ghasemian, Elham, Motaghian, Parisa, Vatanara, Alireza
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Tabriz University of Medical Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961979/
https://ncbi.nlm.nih.gov/pubmed/27478783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2016.029
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