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D-optimal Design for Preparation and Optimization of Fast Dissolving Bosentan Nanosuspension
Purpose: Bosentan is a drug currently taken orally for the treatment of pulmonary arterial hypertension. However, the water solubility of bosentan is very low, resulting in low bioavailability. The aim of this study was preparation and optimization of bosentan nanosuspension to improve solubility an...
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| Publicado no: | Adv Pharm Bull |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Tabriz University of Medical Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961979/ https://ncbi.nlm.nih.gov/pubmed/27478783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2016.029 |
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