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Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction

Substantial efforts have been made to understand the interactions between immune checkpoint receptors and their ligands targeted in immunotherapies against cancer. To carefully characterize the complete network of interactions involved and the binding affinities between their extracellular domains,...

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Publicat a:Nat Commun
Autors principals: Lee, Jung-Rok, Bechstein, Daniel J. B., Ooi, Chin Chun, Patel, Ashka, Gaster, Richard S., Ng, Elaine, Gonzalez, Lino C., Wang, Shan X.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961847/
https://ncbi.nlm.nih.gov/pubmed/27447090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12220
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