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Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction

Substantial efforts have been made to understand the interactions between immune checkpoint receptors and their ligands targeted in immunotherapies against cancer. To carefully characterize the complete network of interactions involved and the binding affinities between their extracellular domains,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Jung-Rok, Bechstein, Daniel J. B., Ooi, Chin Chun, Patel, Ashka, Gaster, Richard S., Ng, Elaine, Gonzalez, Lino C., Wang, Shan X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961847/
https://ncbi.nlm.nih.gov/pubmed/27447090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12220
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