Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade.
The small GTP-binding protein Ras appears to be required for transformation and differentiation induced by tyrosine kinases. The Ras requirement may be limited to a few tyrosine kinase-regulated signaling pathways or may be universal for all tyrosine kinase actions. Because both Ras and the microtub...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1992
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49617/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1495981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.6924 |
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