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Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade.

The small GTP-binding protein Ras appears to be required for transformation and differentiation induced by tyrosine kinases. The Ras requirement may be limited to a few tyrosine kinase-regulated signaling pathways or may be universal for all tyrosine kinase actions. Because both Ras and the microtub...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Robbins, D J, Cheng, M, Zhen, E, Vanderbilt, C A, Feig, L A, Cobb, M H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1495981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.6924
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