Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

Rheumatoid arthritis (RA) is a heterogeneous, prevalent, chronic autoimmune disease characterized by painful swollen joints and significant disabilities. Symptomatic relief can be achieved in up to 50% of patients using biological agents that inhibit tumor necrosis factor (TNF) or other mechanisms o...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Koopman, Frieda A., Chavan, Sangeeta S., Miljko, Sanda, Grazio, Simeon, Sokolovic, Sekib, Schuurman, P. Richard, Mehta, Ashesh D., Levine, Yaakov A., Faltys, Michael, Zitnik, Ralph, Tracey, Kevin J., Tak, Paul P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961187/
https://ncbi.nlm.nih.gov/pubmed/27382171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605635113
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