Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

Rheumatoid arthritis (RA) is a heterogeneous, prevalent, chronic autoimmune disease characterized by painful swollen joints and significant disabilities. Symptomatic relief can be achieved in up to 50% of patients using biological agents that inhibit tumor necrosis factor (TNF) or other mechanisms o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Koopman, Frieda A., Chavan, Sangeeta S., Miljko, Sanda, Grazio, Simeon, Sokolovic, Sekib, Schuurman, P. Richard, Mehta, Ashesh D., Levine, Yaakov A., Faltys, Michael, Zitnik, Ralph, Tracey, Kevin J., Tak, Paul P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961187/
https://ncbi.nlm.nih.gov/pubmed/27382171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605635113
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