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Acute lithium administration selectively lowers tyrosine levels in serum and brain

Lithium exerts anti-dopaminergic behavioral effects. We examined whether some of these might be mediated by changes in brain levels of tyrosine (TYR), the precursor to dopamine. Lithium chloride (LiCl(2)) 3.0 mEq/kg IP acutely lowered serum TYR and the ratio of serum TYR to other large neutral amino...

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Bibliografische gegevens
Gepubliceerd in:Brain Res
Hoofdauteurs: McFarlane, Hewlet G., Steele, John, Vinion, Keenan, Bongiovanni, Rodolfo, Double, Manda, Jaskiw, George E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960976/
https://ncbi.nlm.nih.gov/pubmed/21962398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.08.054
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