Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease

Rationale: Chronic obstructive pulmonary disease (COPD) susceptibility is in part related to genetic variants. Most genetic studies have been focused on genome-wide common variants without a specific focus on coding variants, but common and rare coding variants may also affect COPD susceptibility. O...

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Vydáno v:Am J Respir Crit Care Med
Hlavní autoři: Hobbs, Brian D., Parker, Margaret M., Chen, Han, Lao, Taotao, Hardin, Megan, Qiao, Dandi, Hawrylkiewicz, Iwona, Sliwinski, Pawel, Yim, Jae-Joon, Kim, Woo Jin, Kim, Deog Kyeom, Castaldi, Peter J., Hersh, Craig P., Morrow, Jarrett, Celli, Bartolome R., Pinto-Plata, Victor M., Criner, Gerald J., Marchetti, Nathaniel, Bueno, Raphael, Agustí, Alvar, Make, Barry J., Crapo, James D., Calverley, Peter M., Donner, Claudio F., Lomas, David A., Wouters, Emiel F. M., Vestbo, Jorgen, Paré, Peter D., Levy, Robert D., Rennard, Stephen I., Zhou, Xiaobo, Laird, Nan M., Lin, Xihong, Beaty, Terri H., Silverman, Edwin K., Cho, Michael H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960630/
https://ncbi.nlm.nih.gov/pubmed/26771213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201510-2053OC
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