ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells

Glioma cells with stem cell traits are thought to be responsible for tumor maintenance and therapeutic failure. Such cells can be enriched based on their inherent drug efflux capability mediated by the ABC transporter ABCG2 using the side population assay, and their characteristics include increased...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wee, Boyoung, Pietras, Alexander, Ozawa, Tatsuya, Bazzoli, Elena, Podlaha, Ondrej, Antczak, Christophe, Westermark, Bengt, Nelander, Sven, Uhrbom, Lene, Forsberg-Nilsson, Karin, Djaballah, Hakim, Michor, Franziska, Holland, Eric C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960591/
https://ncbi.nlm.nih.gov/pubmed/27456282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25956
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