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PDGF-B Can Sustain Self-renewal and Tumorigenicity of Experimental Glioma-Derived Cancer-Initiating Cells by Preventing Oligodendrocyte Differentiation

According to the cancer stem cell (CSC)/cancer-initiating cell hypothesis, glioma development is driven by a subpopulation of cells with unique tumor-regenerating capacity. We have characterized sphere-cultured glioma-derived cancer-initiating cells (GICs) from experimental gliomas induced by platel...

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Detalhes bibliográficos
Main Authors: Jiang, Yiwen, Boije, Maria, Westermark, Bengt, Uhrbom, Lene
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114243/
https://ncbi.nlm.nih.gov/pubmed/21677873
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