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Comparative proteomics analysis of global cellular stress responses to hydroxyurea-induced DNA damage in HeLa cells

Both environmental agents and spontaneous cellular events cause serious DNA damage, threatening the integrity of the genome. In response to replication stress or genotoxic agents triggered DNA damage, degradation of p12 subunit of DNA polymerase delta (Pol δ) results in an inter-conversion between h...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: You, Chao, Yang, Yanhua, Zhang, Lei, Chen, Huiqing, Chen, Yan, Chen, Keping, Zhou, Yajing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960130/
https://ncbi.nlm.nih.gov/pubmed/25519465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9832-y
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