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Role of α4-containing GABA(A) receptors in limiting synaptic plasticity and spatial learning of female mice during the pubertal period
Expression of α4βδ GABA(A) receptors (GABARs) increases at the onset of puberty on dendritic spines of CA1 hippocampal pyramidal cells. These receptors reduce activation of NMDA receptors (NMDARs), impair induction of long-term potentiation (LTP) and reduce hippocampal-dependent spatial learning. Th...
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| Publicado no: | Brain Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959998/ https://ncbi.nlm.nih.gov/pubmed/26826007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.01.020 |
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