Pharmacological profile of Ascaris suum ACR‐16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues

BACKGROUND AND PURPOSE: Control of nematode parasite infections relies largely on anthelmintic drugs, several of which act on nicotinic ACh receptors (nAChRs), and there are concerns about the development of resistance. There is an urgent need for development of new compounds to overcome resistance...

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Publicado en:Br J Pharmacol
Autores principales: Abongwa, Melanie, Buxton, Samuel K, Courtot, Elise, Charvet, Claude L, Neveu, Cédric, McCoy, Ciaran J, Verma, Saurabh, Robertson, Alan P, Martin, Richard J
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959957/
https://ncbi.nlm.nih.gov/pubmed/27238203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13524
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