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Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride

BACKGROUND AND PURPOSE: Nitidine chloride (NC), a benzophenanthridine alkaloid, has various biological properties including anticancer and analgesic activities. The aim of the present study was to evaluate the role of organic cation transporter 2 (OCT2) and multidrug and toxin extrusion 1 (MATE1) in...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Li, L P, Song, F F, Weng, Y Y, Yang, X, Wang, K, Lei, H M, Ma, J, Zhou, H, Jiang, H D
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959954/
https://ncbi.nlm.nih.gov/pubmed/27324234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13537
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