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Effect of renal dysfunction in dogs on the disposition and marrow toxicity of melphalan.

The effect of renal failure on melphalan pharmacology and toxicity has been poorly understood. Such information is of interest because melphalan is the most commonly used anticancer drug in the treatment of multiple myeloma, which is frequently associated with renal failure. We have studied the disp...

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Autori principali: Alberts, D. S., Chen, H. G., Benz, D., Mason, N. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1981
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010602/
https://ncbi.nlm.nih.gov/pubmed/7225283
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