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Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

Polycomb Group (PcG) proteins are transcriptional repressors that epigenetically modify chromatin and participate in the establishment and maintenance of cell fates. These proteins play important roles in both stem cell self-renewal and in cancer development. Our understanding of their mechanism of...

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Publicado en:Cell Stem Cell
Main Authors: Sauvageau, Martin, Sauvageau, Guy
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959883/
https://ncbi.nlm.nih.gov/pubmed/20804967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.08.002
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