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Probing the C-terminal domain of lipid-free apoA-I demonstrates the vital role of the H10B sequence repeat in HDL formation

apoA-I plays important structural and functional roles in reverse cholesterol transport. We have described the molecular structure of the N-terminal domain, Δ(185-243) by X-ray crystallography. To understand the role of the C-terminal domain, constructs with sequential elongation of Δ(185-243), by i...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Mei, Xiaohu, Liu, Mingjing, Herscovitz, Haya, Atkinson, David
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959866/
https://ncbi.nlm.nih.gov/pubmed/27317763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M068874
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