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Vaccine-generated lung tissue–resident memory T cells provide heterosubtypic protection to influenza infection

Tissue-resident memory T cells (TRM) are a recently defined, noncirculating subset with the potential for rapid in situ protective responses, although their generation and role in vaccine-mediated immune responses is unclear. Here, we assessed TRM generation and lung-localized protection following a...

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Publicado en:JCI Insight
Main Authors: Zens, Kyra D., Chen, Jun Kui, Farber, Donna L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959801/
https://ncbi.nlm.nih.gov/pubmed/27468427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85832
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