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Reduced generation of lung tissue–resident memory T cells during infancy
Infants suffer disproportionately from respiratory infections and generate reduced vaccine responses compared with adults, although the underlying mechanisms remain unclear. In adult mice, lung-localized, tissue-resident memory T cells (TRMs) mediate optimal protection to respiratory pathogens, and...
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| Published in: | J Exp Med |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5626403/ https://ncbi.nlm.nih.gov/pubmed/28855242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170521 |
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