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Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes

Human mesenchymal stem cell (hMSC) delivery has demonstrated promise in preclinical and clinical trials for myocardial infarction therapy; however, broad acceptance is hindered by limited understanding of hMSC-human cardiomyocyte (hCM) interactions. To better understand the electrophysiological cons...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Mayourian, Joshua, Savizky, Ruben M., Sobie, Eric A., Costa, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959759/
https://ncbi.nlm.nih.gov/pubmed/27454812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005014
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