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Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells

Cardiac cell therapies involving bone marrow-derived human mesenchymal stem cells (hMSCs) have shown promising results, although their mechanisms of action are still poorly understood. Here, we investigated direct interactions between hMSCs and cardiomyocytes in vitro. Using a genetic Ca(2+) indicat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shadrin, Ilya Y., Yoon, Woohyun, Li, Liqing, Shepherd, Neal, Bursac, Nenad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498233/
https://ncbi.nlm.nih.gov/pubmed/26159124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12043
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