The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression

BACKGROUND: Fibroblast growth factor 21 (FGF21), a stress inducible hepatokine, is synthesized in the liver and plays important roles in glucose and lipid metabolism. However, the mechanism of hepatic cannabinoid type 1 (CB1) receptor-mediated induction of FGF21 gene expression is largely unknown. R...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jung, Yoon Seok, Lee, Ji-Min, Kim, Don-Kyu, Lee, Yong-Soo, Kim, Ki-Sun, Kim, Yong-Hoon, Kim, Jina, Lee, Myung-Shik, Lee, In-Kyu, Kim, Seong Heon, Cho, Sung Jin, Jeong, Won-Il, Lee, Chul-Ho, Harris, Robert A., Choi, Hueng-Sik
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959684/
https://ncbi.nlm.nih.gov/pubmed/27455076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159425
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