Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

Bacterial superinfections are a primary cause of death during influenza pandemics and epidemics. Type I interferon (IFN) signaling contributes to increased susceptibility of mice to bacterial superinfection around day 7 post-influenza A virus (IAV) infection. Here we demonstrate that the reduced sus...

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Veröffentlicht in:mBio
Hauptverfasser: Shepardson, Kelly M., Larson, Kyle, Morton, Rachelle V., Prigge, Justin R., Schmidt, Edward E., Huber, Victor C., Rynda-Apple, Agnieszka
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959663/
https://ncbi.nlm.nih.gov/pubmed/27143388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00506-16
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