IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections

Influenza virus infections particularly when followed by bacterial superinfections (BSI) result in significant morbidities and mortalities especially during influenza pandemics. Type I interferons (IFNs) regulate both anti-influenza immunity and host susceptibility to subsequent BSIs. These type I I...

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Pubblicato in:Front Immunol
Autori principali: Shepardson, Kelly M., Larson, Kyle, Johns, Laura L., Stanek, Kayla, Cho, Hanbyul, Wellham, Julia, Henderson, Haley, Rynda-Apple, Agnieszka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237881/
https://ncbi.nlm.nih.gov/pubmed/30473701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02589
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