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Conformational Rearrangements of Individual Nucleotides during RNA-Ligand Binding Are Rate-Differentiated

A pronounced rate differentiation has been found for conformational rearrangements of individual nucleobases that occur during ligand recognition of the preQ(1) class-I riboswitch aptamer from Thermoanaerobacter tengcongensis. Rate measurements rely on the 2ApFold approach by analyzing the fluoresce...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Frener, Marina, Micura, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959565/
https://ncbi.nlm.nih.gov/pubmed/26974261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b11876
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