Functional Expression of the 11 Human Organic Anion Transporting Polypeptides in Insect Cells Reveals that Sodium Fluorescein is a General OATP Substrate

Organic Anion Transporting Polypeptides (OATPs), encoded by genes of the Solute Carrier Organic Anion (SLCO) family, are transmembrane proteins involved in the uptake of various compounds of endogenous or exogenous origin. In addition to their physiological roles, OATPs influence the pharmacokinetic...

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Bibliographic Details
Published in:Biochem Pharmacol
Main Authors: Patik, Izabel, Kovacsics, Daniella, Német, Orsolya, Gera, Melinda, Várady, György, Stieger, Bruno, Hagenbuch, Bruno, Szakács, Gergely, Özvegy-Laczka, Csilla
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959548/
https://ncbi.nlm.nih.gov/pubmed/26415544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.09.015
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