Functional Expression of the 11 Human Organic Anion Transporting Polypeptides in Insect Cells Reveals that Sodium Fluorescein is a General OATP Substrate

Organic Anion Transporting Polypeptides (OATPs), encoded by genes of the Solute Carrier Organic Anion (SLCO) family, are transmembrane proteins involved in the uptake of various compounds of endogenous or exogenous origin. In addition to their physiological roles, OATPs influence the pharmacokinetic...

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Vydáno v:Biochem Pharmacol
Hlavní autoři: Patik, Izabel, Kovacsics, Daniella, Német, Orsolya, Gera, Melinda, Várady, György, Stieger, Bruno, Hagenbuch, Bruno, Szakács, Gergely, Özvegy-Laczka, Csilla
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959548/
https://ncbi.nlm.nih.gov/pubmed/26415544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.09.015
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