Accelerated Blood Clearance Phenomenon Reduces the Passive Targeting of PEGylated Nanoparticles in Peripheral Arterial Disease

Peripheral arterial disease (PAD) is a leading global health concern. Due to limited imaging and therapeutic options, PAD and other ischemia-related diseases may benefit from the use of long circulating nanoparticles as imaging probes and/or drug delivery vehicles. Polyethylene glycol (PEG)-conjugat...

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Publicado en:ACS Appl Mater Interfaces
Main Authors: Im, Hyung-Jun, England, Christopher G., Feng, Liangzhu, Graves, Stephen A., Hernandez, Reinier, Nickles, Robert J., Liu, Zhuang, Lee, Dong Soo, Cho, Steve Y., Cai, Weibo
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959540/
https://ncbi.nlm.nih.gov/pubmed/27340833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.6b05840
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